Web : sysbio.hufs.ac.kr

2021

• M. Shim, J. Lee, D. Kwon, D. Lee, N. Park, Y. Ko and J. Kim Reference-based read clustering improves the de novo genome assembly of microbial strains, Submitted
• S. Yoon, Y. Ko, G. Jeong, K. Lee, J. Lee, M. Solmi, L. Jacob, L. Smith, A. Stickley, A. Carvalho, E. Dragioti,  A. Kronbichler, A. Koyanagi, S. Hong, T. Thompson, H. Oh, G. Pabo, J. Radua, J. Shin Differential Expression of MicroRNAs in Alzheimer's Disease: A Systematic Review and Meta-analysis, The Lancet Psychiatry Submitted
• E. Choi, Y.Ko and M Williams Transcriptional analysis of sweet corn hybrids in response to crowding stress, PLoS ONE, 2021. Jun 16(6).
• Y. Ko,  J. Lee, C. Lee, N. Jeon, K. Lee, J. Oh, A. Kronbichler, M. Saleem, B. Lim, and J. Shin RNA-Seq-based transcriptomic profiling of human podocytes in response to interleukin-4 and dexamethasone: an in vitro model of nephrotic syndrome, Journal of Clinical Medicine, 2021 Feb;10(3):496
• J. Oh, J. Shin, C. Lee, H.Lee, Y. Ko, and J. Lee Clinical application of a phenotype-based NGS panel fo differential diagnosis of inherited kidney disease and the beyond, Clinical Genetics, 2021 Feb;99(2):236-249

2020

• J. Lee, M. Son, C. Son, K. Lee,  Y. Ko, J. Radua,  M. Eisenhut, F. Gressier, A. Koyanagi,  B. Stubbs, M. Solmi, T. Rais, K. Lee,  A. Kronbichler, E. Dragioti, D. Vasconcelos, F. Silva, K. Tizaoui, G. Jeong, J. Kim, A. Brunoni, A. Carvalho, J. Shin, P. Fusar-Poli  Genetic variation and autism: A field synopsis and systematic meta-analysis, Brain Sciences, 10(115):5076, 2020

• Y. Ko Computational drug repositioning : Current progress and challeges, Appl. Sci, 10(15), 5076, 2020
• J. Jeong, M. Kim, J. Lee, H. Lee, Y. Ko, H. Kim, S. Fang ID1-mediated BMP signaling pathway potentiates Glucagon-like peptide-1 secretion in response to nutrient replenishment, International Journal of Molecular Sciences, Int. J. Mol. Sci. 21(11), 3824, 2020
  
• M. Kim,  K. Jung, Y. Ko, I. Kim, K. Hwang,  J. Jang,  J. Shin, and K. Park TNF-α pretreatment improves the survival and function of transplanted human neural progenitor cells following hypoxic-ischemic brain injury, Cells, 9(5), 1195, 2020
• S. Name, K. Lee, Y. Ko, M. Eisenhut, K. Lee,  J. Shin, A. Kronbichler  Understanding the genetics in systematic lupus erythematosus using Bayesian statistics and gene network analysis, Clin Exp Pediatr, doi:190.3345/cep.2020.00633, 2020
• J. Park, K. Lee, B. Jeon, H. Ochs, J. Lee, H. Gee, S. Seo, D, Geum, C. Piccirillo, M. Eisenhut, H. Vliet, J. Lee, A. Kronbichler, Y. Ko,  J. Shin Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome: a systematic review. Autoimmun Rev. 2020 

2019

• Y. Ko, C. Lee, Y. Lee and J. Lee Systematic Approach for Drug Repositioning of Anti-epileptic Drugs., Diagnostics, 9(4), 208, 2019
• S. Baek, S. Oh, D. Kim, K. Kim. K. Boo, Y. Ko,  D. Park and S. Fang RORα Is Crucial for Attenuated Inflammatory Response to Maintain Intestinal Homeostasis.PNAS, 2019
• S. Jang, S. Fang, K. Kim, Y. Ko,  H. Kim. J. Oh, G. Hong, S. Lee, J. Kim, I. Noh and D. Lee Combination treatment with n-3 polyunsaturated fatty acids and ursodeoxycholic acid dissolves cholesterol gallstones in mice. Scientific Reports 9, Article number:12740, 2019
• K. Lee, A. Kronbichler, D. Vasconcelos, F. Silva, Y. Ko, Y. Oh, M. Eisenhut, J. Shin et. al, Genetic Variants in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: A Bayesian Approach and Systematic Review, Journal of Clinical Medicine, 2019
• Y. Ko, J. Kim, and S. Zas Markov chain Monte Carlo simulation of a bayesian mixture model for gene network inference., Genes & Genomics, 2019

2018

• J. Lee, D. Lee, M. Sim, D. Kwon, J. Kim, Y. Ko, and J. Kim mySyntenyPortal: an application package to construct websites for synteny block analysis.,BMC Bioinformatics,19:216, 2018
• M. Kim, K. Jung, I. Kim, I.  Lee, Y. Ko,  J. Shin and K. Park TNF-α induces human neural progenitor cell survival after oxygen-glucose deprivation via NF-κB pathway. Experimental & Molecular Medicine, 50:14, 2018 

2017

• Y. Cho, C. Lee, E. Jeong, M. Kim, J. Hong, Y. Ko, B. Lee, G. Yun, B. Kim, J. Jung, J. Jung and J. Lee Prevalence of Rare Genetic Variations and Their Implications in NGS-data Interpretation. Scientific Reports 7, Article number:9801, 2017
• Y. Ko, C.Lee, H.Lee, M.Lee and J. Lee Clinical application of next-generation sequencing for the diagnosis of segmental neurofibromatosis. Journal of Dermatological Science, 2017

2016

• Y. Ko, M. Cho, J.Lee, and J. Kim Identification of disease comorbidity through hidden molecular mechanisms. Scientific Reports 6, Article number:39433, 2016
• D. Lee, M. Cho, W. Hong, D. Lim, H. Kim, Y. Cho, J. Jeong, B. Choi, Y. Ko, and J. Kim  Evolutionary analyses of Hanwoo (Korean cattle)-specific single-nucleotide polymorphisms and genes using whole-genome resequencing data of a Hanwoo population., Mol. Cells 2016; 39(9): 692~698, 2016  
• J. Lee, W. Hong, M. Cho, M. Sim, D. Lee, Y. Ko , and J. KimSynteny Portal: a web-based application portal for synteny block analysis. Nucleic Acids Research , doi: 10.1093/nar/gkw310, First published online: May 6, 2016
• Y. Ko, C. Lee, M. Moon, G. Hong, C. Cheon, and J. LeeUnravelling the mechanism of action of enzyme replacement therapy in Fabry disease. Journal of Human Genetics, 61:143-149, 2016
• H. Han, H. Shim, D. Shin, J. Shim, Y. Ko, J. Shin, H. Kim, A. Cho, E. Kim, T. Lee, H. Kim, S. Yang, D. Bae, A Yun, S. Kim, C. Kim, H. Cho, B. Kang, S. Shin, and I. Lee TRRUST: a reference database of human transcriptional regulatory interactions. Scientific Reports, 12:11432, 2015